mouse specific caspase 8 Search Results


inhibitor z i e ome t d ome fmk  (R&D Systems)
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Inhibitor Z I E Ome T D Ome Fmk, supplied by R&D Systems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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caspase 8  (Cell Signaling Technology Inc)
96
Cell Signaling Technology Inc caspase 8
Caspase 8, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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human caspase 8  (Proteintech)
96
Proteintech human caspase 8
Human Caspase 8, supplied by Proteintech, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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u0126  (Cell Signaling Technology Inc)
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mouse anti-human caspase-8  (Becton Dickinson)
90
Becton Dickinson mouse anti-human caspase-8
Activation of caspases and poly (ADP-ribose) polymerase (PARP) in MCF-7 and MDA-MB-435 breast cancer cells by SZ-685C. (A) Western blotting analysis of caspases and PARP in MCF-7 and MDA-MB-435 after SZ-685C treatment at different concentrations for 48 h using antibodies against <t>caspase-8,</t> 9, 3 and PARP. GAPDH was used as an internal control. (B) Enzymatic activities of caspases in SZ-685C-treated MCF-7 and MDA-MB-435 cells, as assessed with colorimetric or fluorometric assay. The fold increases in the activities of caspase-8, 9 and 3 were determined by comparison with those of the vehicle-treated control cells. Results are presented as means ± SD. *P < 0.05, **P < 0.01; significant differences compared with the control.
Mouse Anti Human Caspase 8, supplied by Becton Dickinson, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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anti caspase 8 human specific antibody  (Cell Signaling Technology Inc)
99
Cell Signaling Technology Inc anti caspase 8 human specific antibody
Activation of caspases and poly (ADP-ribose) polymerase (PARP) in MCF-7 and MDA-MB-435 breast cancer cells by SZ-685C. (A) Western blotting analysis of caspases and PARP in MCF-7 and MDA-MB-435 after SZ-685C treatment at different concentrations for 48 h using antibodies against <t>caspase-8,</t> 9, 3 and PARP. GAPDH was used as an internal control. (B) Enzymatic activities of caspases in SZ-685C-treated MCF-7 and MDA-MB-435 cells, as assessed with colorimetric or fluorometric assay. The fold increases in the activities of caspase-8, 9 and 3 were determined by comparison with those of the vehicle-treated control cells. Results are presented as means ± SD. *P < 0.05, **P < 0.01; significant differences compared with the control.
Anti Caspase 8 Human Specific Antibody, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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anti-caspase-8 c15 mouse mab ag-20b-0056-c050  (Adipogen)
90
Adipogen anti-caspase-8 c15 mouse mab ag-20b-0056-c050
Activation of caspases and poly (ADP-ribose) polymerase (PARP) in MCF-7 and MDA-MB-435 breast cancer cells by SZ-685C. (A) Western blotting analysis of caspases and PARP in MCF-7 and MDA-MB-435 after SZ-685C treatment at different concentrations for 48 h using antibodies against <t>caspase-8,</t> 9, 3 and PARP. GAPDH was used as an internal control. (B) Enzymatic activities of caspases in SZ-685C-treated MCF-7 and MDA-MB-435 cells, as assessed with colorimetric or fluorometric assay. The fold increases in the activities of caspase-8, 9 and 3 were determined by comparison with those of the vehicle-treated control cells. Results are presented as means ± SD. *P < 0.05, **P < 0.01; significant differences compared with the control.
Anti Caspase 8 C15 Mouse Mab Ag 20b 0056 C050, supplied by Adipogen, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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cleaved caspase 8 asp387  (Cell Signaling Technology Inc)
96
Cell Signaling Technology Inc cleaved caspase 8 asp387
Activation of caspases and poly (ADP-ribose) polymerase (PARP) in MCF-7 and MDA-MB-435 breast cancer cells by SZ-685C. (A) Western blotting analysis of caspases and PARP in MCF-7 and MDA-MB-435 after SZ-685C treatment at different concentrations for 48 h using antibodies against <t>caspase-8,</t> 9, 3 and PARP. GAPDH was used as an internal control. (B) Enzymatic activities of caspases in SZ-685C-treated MCF-7 and MDA-MB-435 cells, as assessed with colorimetric or fluorometric assay. The fold increases in the activities of caspase-8, 9 and 3 were determined by comparison with those of the vehicle-treated control cells. Results are presented as means ± SD. *P < 0.05, **P < 0.01; significant differences compared with the control.
Cleaved Caspase 8 Asp387, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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caspase 8  (ProSci Incorporated)
93
ProSci Incorporated caspase 8
Activation of caspases and poly (ADP-ribose) polymerase (PARP) in MCF-7 and MDA-MB-435 breast cancer cells by SZ-685C. (A) Western blotting analysis of caspases and PARP in MCF-7 and MDA-MB-435 after SZ-685C treatment at different concentrations for 48 h using antibodies against <t>caspase-8,</t> 9, 3 and PARP. GAPDH was used as an internal control. (B) Enzymatic activities of caspases in SZ-685C-treated MCF-7 and MDA-MB-435 cells, as assessed with colorimetric or fluorometric assay. The fold increases in the activities of caspase-8, 9 and 3 were determined by comparison with those of the vehicle-treated control cells. Results are presented as means ± SD. *P < 0.05, **P < 0.01; significant differences compared with the control.
Caspase 8, supplied by ProSci Incorporated, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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antibodies against caspase 8  (Cell Signaling Technology Inc)
96
Cell Signaling Technology Inc antibodies against caspase 8
Activation of caspases and poly (ADP-ribose) polymerase (PARP) in MCF-7 and MDA-MB-435 breast cancer cells by SZ-685C. (A) Western blotting analysis of caspases and PARP in MCF-7 and MDA-MB-435 after SZ-685C treatment at different concentrations for 48 h using antibodies against <t>caspase-8,</t> 9, 3 and PARP. GAPDH was used as an internal control. (B) Enzymatic activities of caspases in SZ-685C-treated MCF-7 and MDA-MB-435 cells, as assessed with colorimetric or fluorometric assay. The fold increases in the activities of caspase-8, 9 and 3 were determined by comparison with those of the vehicle-treated control cells. Results are presented as means ± SD. *P < 0.05, **P < 0.01; significant differences compared with the control.
Antibodies Against Caspase 8, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


Activation of caspases and poly (ADP-ribose) polymerase (PARP) in MCF-7 and MDA-MB-435 breast cancer cells by SZ-685C. (A) Western blotting analysis of caspases and PARP in MCF-7 and MDA-MB-435 after SZ-685C treatment at different concentrations for 48 h using antibodies against caspase-8, 9, 3 and PARP. GAPDH was used as an internal control. (B) Enzymatic activities of caspases in SZ-685C-treated MCF-7 and MDA-MB-435 cells, as assessed with colorimetric or fluorometric assay. The fold increases in the activities of caspase-8, 9 and 3 were determined by comparison with those of the vehicle-treated control cells. Results are presented as means ± SD. *P < 0.05, **P < 0.01; significant differences compared with the control.

Journal: British Journal of Pharmacology

Article Title: SZ-685C, a marine anthraquinone, is a potent inducer of apoptosis with anticancer activity by suppression of the Akt/FOXO pathway

doi: 10.1111/j.1476-5381.2009.00577.x

Figure Lengend Snippet: Activation of caspases and poly (ADP-ribose) polymerase (PARP) in MCF-7 and MDA-MB-435 breast cancer cells by SZ-685C. (A) Western blotting analysis of caspases and PARP in MCF-7 and MDA-MB-435 after SZ-685C treatment at different concentrations for 48 h using antibodies against caspase-8, 9, 3 and PARP. GAPDH was used as an internal control. (B) Enzymatic activities of caspases in SZ-685C-treated MCF-7 and MDA-MB-435 cells, as assessed with colorimetric or fluorometric assay. The fold increases in the activities of caspase-8, 9 and 3 were determined by comparison with those of the vehicle-treated control cells. Results are presented as means ± SD. *P < 0.05, **P < 0.01; significant differences compared with the control.

Article Snippet: Membranes were then incubated overnight at 4°C with the following specific primary antibodies: mouse anti-human caspase-8, mouse anti-human caspase-9 (BD Biosciences, San Jose, CA, USA); rabbit anti-human caspase-3 (Abcam, Cambridge, MA, USA); rabbit anti-human poly (ADP-ribose) polymerase (PARP), rabbit anti-human phospho-Akt (ser473), rabbit anti-human Akt, rabbit anti-human phospho-FOXO3a (ser253), rabbit anti-human FOXO3a, rabbit anti-human phospho-FOXO1 (ser256), rabbit anti-human Bim (Cell Signaling Technology, Beverly, MA, USA); and mouse anti-human GAPDH (ProteinTech, Chicago, IL, USA).

Techniques: Activation Assay, Western Blot